Nadia El-Mabrouk and her team, the
LBIT laboratory, developed Synesth, a tool for
super-reconciliation : merging gene
trees and species trees into a global evolutionary history, to better understand how genes evolve
across species.
Even among the Pareto-optimal histories there can be a billion or more of them, far too many to
show to a user. My project was to return only "representative" solutions, which first required
defining what representative means - an approach close to operations research and optimization.
Started as an optional course project during the winter 2024 session, it continued from May to July
with the simulations validating the approach and the preparation of the poster presented at
ISMB 2024.